Poppers: Difference between revisions

added medical cases of eye issues to incidents section
(Added notes about eye damage)
Tags: Visual edit Mobile edit Mobile web edit
(added medical cases of eye issues to incidents section)
Tags: Visual edit Mobile edit Mobile web edit
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In some individuals or in high doses, poppers can cause vomiting, methemoglobinemia, hypoxemia, reduced oxygen level in the blood, and unconsciousness<ref name=":0">{{Cite journal |last=Barry |first=Katherine |last2=McAteer |first2=Kristina E. |date=2023-04-03 |title=Syncope and Methemoglobinemia Preceded by Amyl Nitrite 'Popper' Inhalation |url=https://pubmed.ncbi.nlm.nih.gov/36989098/ |journal=Rhode Island Medical Journal (2013) |volume=106 |issue=3 |pages=49–51 |issn=2327-2228 |pmid=36989098}}</ref> which can persist for an extended time even after popper use is stopped.<ref name=":1">{{Cite journal |last=Olazagasti |first=Coral |last2=Paralkar |first2=Janvi |last3=Vishnevetsky |first3=Michael |last4=Chakravarti |first4=Aloke |last5=Sulica |first5=Roxana |last6=Favila |first6=Kristine |date=2016-10 |title=Poppers Not Only Make You High: A Rare Case of Amyl Nitrate-Induced Hypoxia |url=https://doi.org/10.1016/j.chest.2016.08.1216 |journal=Chest |volume=150 |issue=4 |pages=1108A |doi=10.1016/j.chest.2016.08.1216 |issn=0012-3692}}</ref>
In some individuals or in high doses, poppers can cause vomiting, methemoglobinemia, hypoxemia, reduced oxygen level in the blood, and unconsciousness<ref name=":0">{{Cite journal |last=Barry |first=Katherine |last2=McAteer |first2=Kristina E. |date=2023-04-03 |title=Syncope and Methemoglobinemia Preceded by Amyl Nitrite 'Popper' Inhalation |url=https://pubmed.ncbi.nlm.nih.gov/36989098/ |journal=Rhode Island Medical Journal (2013) |volume=106 |issue=3 |pages=49–51 |issn=2327-2228 |pmid=36989098}}</ref> which can persist for an extended time even after popper use is stopped.<ref name=":1">{{Cite journal |last=Olazagasti |first=Coral |last2=Paralkar |first2=Janvi |last3=Vishnevetsky |first3=Michael |last4=Chakravarti |first4=Aloke |last5=Sulica |first5=Roxana |last6=Favila |first6=Kristine |date=2016-10 |title=Poppers Not Only Make You High: A Rare Case of Amyl Nitrate-Induced Hypoxia |url=https://doi.org/10.1016/j.chest.2016.08.1216 |journal=Chest |volume=150 |issue=4 |pages=1108A |doi=10.1016/j.chest.2016.08.1216 |issn=0012-3692}}</ref>


Poppers containing isopropyl nitrite can cause damage to the fovea and can cause significant visual disturbance<ref>{{Cite journal |last=Rewbury |first=Rebecca |last2=Hughes |first2=Edward |last3=Purbrick |first3=Robert |last4=Prior |first4=Stephen |last5=Baron |first5=Mark |date=2017-11-01 |title=Poppers: legal highs with questionable contents? A case series of poppers maculopathy |url=https://bjo.bmj.com/content/101/11/1530 |journal=British Journal of Ophthalmology |language=en |volume=101 |issue=11 |pages=1530–1534 |doi=10.1136/bjophthalmol-2016-310023 |issn=0007-1161 |pmid=28396339}}</ref>. There isn't an easy way to verify if a bottle contains isopropyl nitrite without a lab since product labels may be incorrect, misleading,  or missing (e.g. unlabeled brown bottle).
Poppers containing isopropyl nitrite can cause damage to the fovea and can cause significant visual disturbance<ref name=":2">{{Cite journal |last=Rewbury |first=Rebecca |last2=Hughes |first2=Edward |last3=Purbrick |first3=Robert |last4=Prior |first4=Stephen |last5=Baron |first5=Mark |date=2017-11-01 |title=Poppers: legal highs with questionable contents? A case series of poppers maculopathy |url=https://bjo.bmj.com/content/101/11/1530 |journal=British Journal of Ophthalmology |language=en |volume=101 |issue=11 |pages=1530–1534 |doi=10.1136/bjophthalmol-2016-310023 |issn=0007-1161 |pmid=28396339}}</ref>. There isn't an easy way to verify if a bottle contains isopropyl nitrite without a lab since product labels may be incorrect, misleading,  or missing (e.g. unlabeled brown bottle).


Poppers can cause chemical burns if the liquid becomes exposed to skin or sinuses.
Poppers can cause chemical burns if the liquid becomes exposed to skin or sinuses.
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* 44yr old male in the ER with hypoxemia, methemoglobinemia, unresponsive, stopped heart (1995)<ref>{{Cite journal |last=Edwards |first=R J |last2=Ujma |first2=J |date=1995-06 |title=Extreme methaemoglobinaemia secondary to recreational use of amyl nitrite. |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1342554/ |journal=Journal of Accident & Emergency Medicine |volume=12 |issue=2 |pages=138–142 |issn=1351-0622 |pmc=1342554 |pmid=7582412}}</ref>
* 44yr old male in the ER with hypoxemia, methemoglobinemia, unresponsive, stopped heart (1995)<ref>{{Cite journal |last=Edwards |first=R J |last2=Ujma |first2=J |date=1995-06 |title=Extreme methaemoglobinaemia secondary to recreational use of amyl nitrite. |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1342554/ |journal=Journal of Accident & Emergency Medicine |volume=12 |issue=2 |pages=138–142 |issn=1351-0622 |pmc=1342554 |pmid=7582412}}</ref>
* 34yr old male in the ER with hypoxemia and methemoglobinemia for 4 days (2012)<ref>{{Cite journal |last=Wong |first=Anselm |last2=Koutsogiannis |first2=Zeff |last3=Greene |first3=Shaun |last4=McIntyre |first4=Shona |date=2013-03-01 |title=A case of hemolysis and methemoglobinemia following amyl nitrite use in an individual with G6PD deficiency |url=https://www.sciencedirect.com/science/article/pii/S2211558713000071 |journal=Journal of Acute Medicine |volume=3 |issue=1 |pages=23–25 |doi=10.1016/j.jacme.2012.12.005 |issn=2211-5587}}</ref>
* 34yr old male in the ER with hypoxemia and methemoglobinemia for 4 days (2012)<ref>{{Cite journal |last=Wong |first=Anselm |last2=Koutsogiannis |first2=Zeff |last3=Greene |first3=Shaun |last4=McIntyre |first4=Shona |date=2013-03-01 |title=A case of hemolysis and methemoglobinemia following amyl nitrite use in an individual with G6PD deficiency |url=https://www.sciencedirect.com/science/article/pii/S2211558713000071 |journal=Journal of Acute Medicine |volume=3 |issue=1 |pages=23–25 |doi=10.1016/j.jacme.2012.12.005 |issn=2211-5587}}</ref>
* 12 cases of impared vision presenting to an eye hospital (2017)<ref name=":2" />


== External links ==
== External links ==
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