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GHB: Difference between revisions
Draft of background section
(Created page with "{{Infobox drug | other_names = γ-Hydroxybutyric acid, gamma-hydroxybutyric acid, GHB, 4-hydroxybutanoic acid | image_file = | image_caption = | health_risk = High | addiction_risk = Moderate | legal_risk = High | link_psychonautwiki = https://psychonautwiki.org/wiki/GHB | link_erowid = https://erowid.org/chemicals/ghb/ghb.shtml }} '''γ-Hydroxybutyric acid''', also known as '''''gamma''-hydroxybutyric acid''', '''GHB''', or '''4-hydroxybutanoic acid''', is a depressa...") |
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=== Medical uses === | === Medical uses === | ||
In the United States, GHB is a schedule I controlled substance (defined as having no current accepted medical use). However, GHB does have FDA-approval as an orphan drug to treat narcolepsy with a specific formulation which is classified as schedule III.<ref>{{Cite web |title= |url=https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=530216}}</ref> | |||
GHB was previously used as a general anesthetic, but was abandoned due to a high incidence of myoclonic seizures and vomiting.<ref>{{Cite journal |last=Kam |first=P. C. |last2=Yoong |first2=F. F. |date=1998-12 |title=Gamma-hydroxybutyric acid: an emerging recreational drug |url=https://pubmed.ncbi.nlm.nih.gov/10193223 |journal=Anaesthesia |volume=53 |issue=12 |pages=1195–1198 |doi=10.1046/j.1365-2044.1998.00603.x |issn=0003-2409 |pmid=10193223}}</ref> These side effects correlate closely to common signs of GHB overdose when used recreationally. | |||
=== Mechanism of action === | === Mechanism of action === | ||