Erectile dysfunction drugs: Difference between revisions

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{{Infobox drug
{{Infobox drug
| other_names =  
| other_names = sildenafil citrate, Viagra
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| image_file =  
| image_caption =  
| image_caption =  
| health_risk =  
| health_risk = Mild
| addiction_risk =  
| addiction_risk =  
| legal_risk =  
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Sildenafil (brand name(s): Viagra, Kamagra) is a drug used to treat erectile dysfunction.
Sildenafil is a drug used to treat erectile dysfunction. It is prescribed under brand names such as ''Viagra'' and ''Kamagra''.


== Background<!-- Provide background information for this drug. --> ==
== Background<!-- Provide background information for this drug. --> ==


=== Medical uses ===
=== Medical uses ===
In addition to erectile dysfunction, sildenafil is used to treat pulmonary arterial hypertension in men and women.<ref>{{Cite web |title=Sildenafil (oral route) - Side effects & dosage |url=https://www.mayoclinic.org/drugs-supplements/sildenafil-oral-route/description/drg-20066989 |access-date=2025-11-06 |website=Mayo Clinic |language=en}}</ref>


=== Mechanism of action ===
=== Mechanism of action ===
Sildenafil is an inhibitor of phosphodiesterase 5 (PDE5), an enzyme that regulates blood flow to the penis.


== Appeal<!-- Describe the reasons why people use this drug with kink. --> ==
== Appeal<!-- Describe the reasons why people use this drug with kink. --> ==
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== Risks<!-- Describe the risks of this drug. --> ==
== Risks<!-- Describe the risks of this drug. --> ==
You should check the notes in the medication for side effects, different "fillers" for tablets can have different side effects.
Check the notes in the medication for side effects. Different "fillers" for tablets can have different side effects.


If it affects your blood pressure, it can make you feel spaced out and other symptoms (feeling weak, sick blurred vision, fainting), in this case you should stop further sexual and BDSM activities, and ensure you are somewhere safe in case you pass out.
If it affects your blood pressure, it can make you feel spaced out and other symptoms (feeling weak, sick blurred vision, fainting), in this case you should stop further sexual and BDSM activities, and ensure you are somewhere safe in case you pass out.


if you have a prolonged or sometimes painful erection, especially if it lasts for more than 2 hours, call emergency services<ref>{{Cite web |date=2022-03-03 |title=Side effects of sildenafil |url=https://www.nhs.uk/medicines/sildenafil-viagra/side-effects-of-sildenafil/ |access-date=2024-02-16 |website=nhs.uk}}</ref>.
If experiencing prolonged or painful erection, especially if it lasts for more than 2 hours, call emergency services<ref>{{Cite web |date=2022-03-03 |title=Side effects of sildenafil |url=https://www.nhs.uk/medicines/sildenafil-viagra/side-effects-of-sildenafil/ |access-date=2024-02-16 |website=nhs.uk}}</ref>.


=== Drug interactions<!-- Describe the interactions of this drug. --> ===
=== Drug interactions<!-- Describe the interactions of this drug. --> ===

Revision as of 01:59, 6 November 2025

Erectile dysfunction drugs
Other names sildenafil citrate, Viagra
Health risk Mild
Addiction risk
Legal risk

Sildenafil is a drug used to treat erectile dysfunction. It is prescribed under brand names such as Viagra and Kamagra.

Background

Medical uses

In addition to erectile dysfunction, sildenafil is used to treat pulmonary arterial hypertension in men and women.[1]

Mechanism of action

Sildenafil is an inhibitor of phosphodiesterase 5 (PDE5), an enzyme that regulates blood flow to the penis.

Appeal

Dosing

Risks

Check the notes in the medication for side effects. Different "fillers" for tablets can have different side effects.

If it affects your blood pressure, it can make you feel spaced out and other symptoms (feeling weak, sick blurred vision, fainting), in this case you should stop further sexual and BDSM activities, and ensure you are somewhere safe in case you pass out.

If experiencing prolonged or painful erection, especially if it lasts for more than 2 hours, call emergency services[2].

Drug interactions

Addiction

Risk mitigation

Sildenafil should never be used with poppers as together they can cause fatal drop in blood pressure. It should also not be used in combination with other medicines being used to treat blood pressure.

If the user is feeling symptoms of low blood pressure:

  • Seek medical attention
  • Lay down
  • Sitting up or standing up suddenly can worsen lightheadedness or cause fainting.
  • Drink water
  • Do not consume alcohol or other substances

Known incidents

Medical case reports

RACKWiki incident reports

References

https://www.nhs.uk/conditions/low-blood-pressure-hypotension/

  1. "Sildenafil (oral route) - Side effects & dosage". Mayo Clinic. Retrieved 2025-11-06.
  2. "Side effects of sildenafil". nhs.uk. 2022-03-03. Retrieved 2024-02-16.