GHB: Difference between revisions
(Created page with "{{Infobox drug | other_names = γ-Hydroxybutyric acid, gamma-hydroxybutyric acid, GHB, 4-hydroxybutanoic acid | image_file = | image_caption = | health_risk = High | addiction_risk = Moderate | legal_risk = High | link_psychonautwiki = https://psychonautwiki.org/wiki/GHB | link_erowid = https://erowid.org/chemicals/ghb/ghb.shtml }} '''γ-Hydroxybutyric acid''', also known as '''''gamma''-hydroxybutyric acid''', '''GHB''', or '''4-hydroxybutanoic acid''', is a depressa...") |
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=== Medical uses === | === Medical uses === | ||
In the United States, GHB is a schedule I controlled substance (defined as having no current accepted medical use). However, GHB does have FDA-approval as an orphan drug to treat narcolepsy with a specific formulation which is classified as schedule III.<ref>{{Cite web |title= |url=https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=530216}}</ref> | |||
GHB was previously used as a general anesthetic, but was abandoned due to a high incidence of myoclonic seizures and vomiting.<ref>{{Cite journal |last=Kam |first=P. C. |last2=Yoong |first2=F. F. |date=1998-12 |title=Gamma-hydroxybutyric acid: an emerging recreational drug |url=https://pubmed.ncbi.nlm.nih.gov/10193223 |journal=Anaesthesia |volume=53 |issue=12 |pages=1195–1198 |doi=10.1046/j.1365-2044.1998.00603.x |issn=0003-2409 |pmid=10193223}}</ref> These side effects correlate closely to common signs of GHB overdose when used recreationally. | |||
=== Mechanism of action === | === Mechanism of action === | ||
Revision as of 22:37, 27 October 2025
GHB
| Other names | γ-Hydroxybutyric acid, gamma-hydroxybutyric acid, GHB, 4-hydroxybutanoic acid |
|---|---|
| Health risk | High |
| Addiction risk | Moderate |
| Legal risk | High |
| External links | PsychonautWiki Erowid |
γ-Hydroxybutyric acid, also known as gamma-hydroxybutyric acid, GHB, or 4-hydroxybutanoic acid, is a depressant used recreationally for its alcohol-like effects.
Background
Medical uses
In the United States, GHB is a schedule I controlled substance (defined as having no current accepted medical use). However, GHB does have FDA-approval as an orphan drug to treat narcolepsy with a specific formulation which is classified as schedule III.[1]
GHB was previously used as a general anesthetic, but was abandoned due to a high incidence of myoclonic seizures and vomiting.[2] These side effects correlate closely to common signs of GHB overdose when used recreationally.
Mechanism of action
Appeal
Dosing
Risks
Drug interactions
Addiction
Risk mitigation
Known incidents
Medical case reports
RACKWiki incident reports
References
- ↑ https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=530216.
{{cite web}}: Missing or empty|title=(help) - ↑ Kam, P. C.; Yoong, F. F. (1998-12). "Gamma-hydroxybutyric acid: an emerging recreational drug". Anaesthesia. 53 (12): 1195–1198. doi:10.1046/j.1365-2044.1998.00603.x. ISSN 0003-2409. PMID 10193223.
{{cite journal}}: Check date values in:|date=(help)